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1

The impact of increasing heavy metal stress on the diversity and structure of the bacterial and actinobacterial communities of metallophytic grassland soil

Lisa Bamborough, Stephen P. Cummings

Journal:

Biology and Fertility of Soils

Year:

2009

Language:

english

File:

PDF, 166 KB

english, 2009

2

The prion folding problem

Paul M Harrison, Paul Bamborough, Valerie Daggett, Stanley B Prusiner, Fred E Cohen

Journal:

Current Opinion in Structural Biology

Year:

1997

Language:

english

File:

PDF, 722 KB

english, 1997

3

The interleukin-2 and interleukin-4 receptors studied by molecular modelling

Paul Bamborough, Charles JR Hedgecock, W.Graham Richards

Journal:

Year:

1994

Language:

english

File:

PDF, 1.58 MB

english, 1994

4

Fragments in bromodomain drug discovery

Bamborough, Paul, Chung, Chun-wa

Journal:

Year:

2015

Language:

english

File:

PDF, 4.35 MB

english, 2015

5

Identification of Candidate Proteins Binding to Prion Protein: Volume 3, Number 4 (1997), pages 339–355

Fruma Yehiely, Paul Bamborough, Maria Da Costa, Billie J. Perry, Gopal Thinakaran, Fred E. Cohen, George A. Carlson, Stanley B. Prusiner

Journal:

Neurobiology of Disease

Year:

2002

Language:

english

File:

PDF, 21 KB

english, 2002

6

Robert Burton's Astrological Notebook

J. B. Bamborough and J. C. Eade

Journal:

The Review of English Studies

Year:

1981

Language:

english

File:

PDF, 466 KB

english, 1981

7

ROBERT BURTON'S ASTROLOGICAL NOTEBOOK

BAMBOROUGH, J. B.

Journal:

The Review of English Studies

Year:

1981

Language:

english

File:

PDF, 4.80 MB

english, 1981

8

A Chemical Probe for the ATAD2 Bromodomain

Bamborough, Paul, Chung, Chun-wa, Demont, Emmanuel H., Furze, Rebecca C., Bannister, Andrew J., Che, Ka Hing, Diallo, Hawa, Douault, Clement, Grandi, Paola, Kouzarides, Tony, Michon, Anne-Marie, Mitch

Journal:

Angewandte Chemie International Edition

Year:

2016

Language:

english

File:

PDF, 1.45 MB

english, 2016

9

Identification of Candidate Proteins Binding to Prion Protein

Fruma Yehiely, Paul Bamborough, Maria Da Costa, Billie J. Perry, Gopal Thinakaran, Fred E. Cohen, George A. Carlson, Stanley B. Prusiner

Journal:

Neurobiology of Disease

Year:

1997

Language:

english

File:

PDF, 323 KB

english, 1997

10

Biphenyl amide p38 kinase inhibitors 3: Improvement of cellular and in vivo activity

Richard Angell, Nicola M. Aston, Paul Bamborough, Jacky B. Buckton, Stuart Cockerill, Suzanne J. deBoeck, Chris D. Edwards, Duncan S. Holmes, Katherine L. Jones, Dramane I. Laine, Shila Patel, Penny A

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2008

Language:

english

File:

PDF, 358 KB

english, 2008

11

Reply

BAMBOROUGH, J. B.

Journal:

Notes and Queries

Year:

2000

Language:

english

File:

PDF, 69 KB

english, 2000

12

REVIEWS

BAMBOROUGH, J. B.

Journal:

The Review of English Studies

Year:

1963

Language:

english

File:

PDF, 885 KB

english, 1963

13

A130 STIMULUS CONTROL OF HUMAN SELECTIVE ATTENTION AND INSTRUMENTAL AVOIDANCE BEHAVIOUR DEPENDS UPON EXPLICIT CONTINGENCY KNOWLEDGE

Hogarth, L., Dickinson, A., Hutton, S.B., Bamborough, H., Duka, T.

Journal:

Behavioural Pharmacology

Year:

2005

Language:

english

File:

PDF, 166 KB

english, 2005

14

Correction to The Discovery of Novel Antimalarial Aminoxadiazoles as a Promising Nonendoperoxide Scaffold

Sandoval, Elena, Lafuente-Monasterio, María José, Almela, María J., Castañeda, Pablo, Jiménez Díaz, María Belén, Martínez-Martínez, María S., Vidal, Jaume, Angulo-Barturen, Íñigo, Bamborough, Paul, Bu

Journal:

Journal of Medicinal Chemistry

Year:

2017

Language:

english

File:

PDF, 135 KB

english, 2017

15

The Optimisation of a Novel, Weak Bromo and Extra Terminal Domain (BET) Bromodomain Fragment Ligand to a Potent and Selective Second Bromodomain (BD2) Inhibitor

Seal, Jonathan Thomas, Atkinson, Stephen J., Aylott, Helen, Bamborough, Paul, Chung, Chun-wa, Copley, Royston C. B., Gordon, Laurie J., Grandi, Paola, Gray, James R. J., Harrison, Lee A, Hayhow, Thoma

Journal:

Journal of Medicinal Chemistry

Year:

2020

File:

PDF, 1.05 MB

2020

16

Tertiary structure of calcineurin B by homology modeling

Susan West, Paul Bamborough, Roger Tully

Journal:

Journal of Molecular Graphics

Year:

1993

Language:

english

File:

PDF, 825 KB

english, 1993

17

Selectivity of Kinase Inhibitor Fragments

Bamborough, Paul, Brown, Murray J., Christopher, John A., Chung, Chun-wa, Mellor, Geoff W.

Journal:

Journal of Medicinal Chemistry

Year:

2011

Language:

english

File:

PDF, 3.16 MB

english, 2011

18

Naphthyridines as Novel BET Family Bromodomain Inhibitors

Mirguet, Olivier, Lamotte, Yann, Chung, Chun-wa, Bamborough, Paul, Delannée, Delphine, Bouillot, Anne, Gellibert, Françoise, Krysa, Gael, Lewis, Antonia, Witherington, Jason, Huet, Pascal, Dudit, Yann

Journal:

Year:

2014

Language:

english

File:

PDF, 996 KB

english, 2014

19

Selective targeting of BD1 and BD2 of the BET proteins in cancer and immuno-inflammation

Gilan, Omer, Rioja, Inmaculada, Knezevic, Kathy, Bell, Matthew J., Yeung, Miriam M., Harker, Nicola R., Lam, Enid Y. N., Chung, Chun-wa, Bamborough, Paul, Petretich, Massimo, Urh, Marjeta, Atkinson, S

Journal:

Year:

2020

Language:

english

File:

PDF, 3.66 MB

english, 2020

20

Kinase array design, back to front: Biaryl amides

Ian Baldwin, Paul Bamborough, Claudine G. Haslam, Suchete S. Hunjan, Tim Longstaff, Christopher J. Mooney, Shila Patel, Jo Quinn, Don O. Somers

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2008

Language:

english

File:

PDF, 705 KB

english, 2008

21

Mapping the kinase domain of janus kinase 3

Christopher Adams, David J. Aldous, Shelley Amendola, Paul Bamborough, Colin Bright, Sarah Crowe, Paul Eastwood, Garry Fenton, Martyn Foster, Trevor K.P. Harrison, Sue King, Justine Lai, Christopher L

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2003

Language:

english

File:

PDF, 332 KB

english, 2003

22

Fragment-Based Discovery of Bromodomain Inhibitors Part 2: Optimization of Phenylisoxazole Sulfonamides

Bamborough, Paul, Diallo, Hawa, Goodacre, Jonathan D., Gordon, Laurie, Lewis, Antonia, Seal, Jonathan T., Wilson, David M., Woodrow, Michael D., Chung, Chun-wa

Journal:

Journal of Medicinal Chemistry

Year:

2012

Language:

english

File:

PDF, 773 KB

english, 2012

23

Substrate specificity and inhibitors of LRRK2, a protein kinase mutated in Parkinson's disease

Nichols, R. Jeremy, Dzamko, Nicolas, Hutti, Jessica E., Cantley, Lewis C., Deak, Maria, Moran, Jennifer, Bamborough, Paul, Reith, Alastair D., Alessi, Dario R.

Journal:

Biochemical Journal

Year:

2009

Language:

english

File:

PDF, 1.56 MB

english, 2009

24

Biphenyl amide p38 kinase inhibitors 1: Discovery and binding mode

Richard M. Angell, Paul Bamborough, Anne Cleasby, Stuart G. Cockerill, Katherine L. Jones, Christopher J. Mooney, Donald O. Somers, Ann L. Walker

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2008

Language:

english

File:

PDF, 719 KB

english, 2008

25

p38α Mitogen-Activated Protein Kinase Inhibitors: Optimization of a Series of Biphenylamides to Give a Molecule Suitable for Clinical Progression

Aston, Nicola M., Bamborough, Paul, Buckton, Jacqueline B., Edwards, Christopher D., Holmes, Duncan S., Jones, Katherine L., Patel, Vipulkumar K., Smee, Penny A., Somers, Donald O., Vitulli, Giovanni,

Journal:

Journal of Medicinal Chemistry

Year:

2009

Language:

english

File:

PDF, 2.37 MB

english, 2009

26

REVIEWS

BAMBOROUGH, J. B.

Journal:

The Review of English Studies

Year:

1980

Language:

english

File:

PDF, 183 KB

english, 1980

27

Ben Jonson: His Vision and His Artby Alexander Leggatt

Review by: J. B. Bamborough

Journal:

The Review of English Studies

Year:

1983

Language:

english

File:

PDF, 379 KB

english, 1983

28

Biphenyl amide p38 kinase inhibitors 2: Optimisation and SAR

Richard M. Angell, Tony D. Angell, Paul Bamborough, David Brown, Murray Brown, Jacky B. Buckton, Stuart G. Cockerill, Chris D. Edwards, Katherine L. Jones, Tim Longstaff, Penny A. Smee, Kathryn J. Smi

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2008

Language:

english

File:

PDF, 338 KB

english, 2008

29

Identification of 2-(4-pyridyl)thienopyridinones as GSK-3β inhibitors

Gabriella Gentile, Giovanni Bernasconi, Alfonso Pozzan, Giancarlo Merlo, Paola Marzorati, Paul Bamborough, Benjamin Bax, Angela Bridges, Caroline Brough, Paul Carter, Geoffrey Cutler, Margarete Neu, M

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2011

Language:

english

File:

PDF, 720 KB

english, 2011

30

Discovery of I-BRD9, a Selective Cell Active Chemical Probe for Bromodomain Containing Protein 9 Inhibition

Theodoulou, Natalie H., Bamborough, Paul, Bannister, Andrew J., Becher, Isabelle, Bit, Rino A., Che, Ka Hing, Chung, Chun-wa, Dittmann, Antje, Drewes, Gerard, Drewry, David H., Gordon, Laurie, Grandi,

Journal:

Journal of Medicinal Chemistry

Year:

2015

Language:

english

File:

PDF, 6.90 MB

english, 2015

31

Progress Towards the Development of Anti-Inflammatory Inhibitors of IKKβ

P. Bamborough, J. Callahan, J. Christopher, J. Kerns, J. Liddle, D. Miller, M. Morse, W. Rumsey, R. Williamson

Year:

2009

Language:

english

File:

PDF, 434 KB

english, 2009

32

Structure-Based Design of a Bromodomain and Extraterminal Domain (BET) Inhibitor Selective for the N-Terminal Bromodomains That Retains an Anti-inflammatory and Antiproliferative Phenotype

Wellaway, Christopher R., Bamborough, Paul, Bernard, Sharon G., Chung, Chun-wa, Craggs, Peter D., Cutler, Leanne, Demont, Emmanuel H., Evans, John P., Gordon, Laurie, Karamshi, Bhumika, Lewis, Antonia

Journal:

Journal of Medicinal Chemistry

Year:

2020

File:

PDF, 6.80 MB

2020

33

The discovery of 2-amino-3,5-diarylbenzamide inhibitors of IKK-α and IKK-β kinases

John A. Christopher, Barbara G. Avitabile, Paul Bamborough, Aurelie C. Champigny, Geoffrey J. Cutler, Susan L. Dyos, Ken G. Grace, Jeffrey K. Kerns, Jeremy D. Kitson, Geoffrey W. Mellor, James V. More

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2007

Language:

english

File:

PDF, 196 KB

english, 2007

34

Molecular modeling of the GM-CSF and IL-3 receptor complexes

P.D. Lyne, P. Bamborough, D. Duncan, W.G. Richards

Journal:

Protein Science

Year:

1995

Language:

english

File:

PDF, 7.73 MB

english, 1995

35

System-based drug discovery within the human kinome

Bamborough, Paul

Journal:

Expert Opinion on Drug Discovery

Year:

2012

Language:

english

File:

PDF, 627 KB

english, 2012

36

REVIEWS

BAMBOROUGH, J. B.

Journal:

The Review of English Studies

Year:

1962

Language:

english

File:

PDF, 138 KB

english, 1962

37

J. Middleton Murry. Selected Criticismby Richard Rees; J. Middleton Murry

Review by: J. B. Bamborough

Journal:

The Review of English Studies

Year:

1962

Language:

english

File:

PDF, 331 KB

english, 1962

38

A Qualified Success: Discovery of a New Series of ATAD2 Bromodomain Inhibitors with a Novel Binding Mode Using High-Throughput Screening and Hit Qualification

Bamborough, Paul, Chung, Chun-wa, Demont, Emmanuel H., Bridges, Angela M., Craggs, Peter D., Dixon, David P., Francis, Peter, Furze, Rebecca C., Grandi, Paola, Jones, Emma J., Karamshi, Bhumika, Locke

Journal:

Journal of Medicinal Chemistry

Year:

2019

Language:

english

File:

PDF, 5.53 MB

english, 2019

39

CDK12 inhibition reduces abnormalities in cells from patients with myotonic dystrophy and in a mouse model

Ketley, Ami, Wojciechowska, Marzena, Ghidelli-Disse, Sonja, Bamborough, Paul, Ghosh, Tushar K., Morato, Marta Lopez, Sedehizadeh, Saam, Malik, Naveed Altaf, Tang, Zhenzhi, Powalowska, Paulina, Tanner,

Journal:

Science Translational Medicine

Year:

2020

File:

PDF, 1.31 MB

2020

40

Pyrrolidine-5,5- trans -lactams. 4. Incorporation of a P3/P4 Urea Leads to Potent Intracellular Inhibitors of Hepatitis C Virus NS3/4A Protease

Slater, Martin J., Amphlett, Elizabeth M., Andrews, David M., Bamborough, Paul, Carey, Seb J., Johnson, Martin R., Jones, Paul S., Mills, Gail, Parry, Nigel R., Stewart, Alan J., Skarzynski, Tadeusz

Journal:

Organic Letters

Year:

2003

Language:

english

File:

PDF, 97 KB

english, 2003

41

REVIEWS

BAMBOROUGH, J. B.

Journal:

The Review of English Studies

Year:

1959

Language:

english

File:

PDF, 206 KB

english, 1959

42

Jonson and the Comic Truthby John J. Enck;Shakespeare and Jonsonby S. Musgrove

Review by: J. B. Bamborough

Journal:

The Review of English Studies

Year:

1959

Language:

english

File:

PDF, 447 KB

english, 1959

43

A Chemical Probe for the ATAD2 Bromodomain

Bamborough, Paul, Chung, Chun-wa, Demont, Emmanuel H., Furze, Rebecca C., Bannister, Andrew J., Che, Ka Hing, Diallo, Hawa, Douault, Clement, Grandi, Paola, Kouzarides, Tony, Michon, Anne-Marie, Mitch

Journal:

Angewandte Chemie

Year:

2016

Language:

english

File:

PDF, 2.49 MB

english, 2016

44

4-Phenyl-7-azaindoles as potent and selective IKK2 inhibitors

John Liddle, Paul Bamborough, Michael D. Barker, Sebastien Campos, Rick P.C. Cousins, Geoffrey J. Cutler, Heather Hobbs, Duncan S. Holmes, Chris Ioannou, Geoff W. Mellor, Mary A. Morse, Jeremy J. Payn

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2009

Language:

english

File:

PDF, 1.09 MB

english, 2009

45

Discovery of 6-Aryl-7-alkoxyisoquinoline Inhibitors of IκB Kinase-β (IKK-β)

Christopher, John A., Bamborough, Paul, Alder, Catherine, Campbell, Amanda, Cutler, Geoffrey J., Down, Kenneth, Hamadi, Ahmed M., Jolly, Adrian M., Kerns, Jeffrey K., Lucas, Fiona S.

Journal:

Journal of Medicinal Chemistry

Year:

2009

Language:

english

File:

PDF, 511 KB

english, 2009

46

The Discovery of I-BET726 (GSK1324726A), a Potent Tetrahydroquinoline ApoA1 Up-Regulator and Selective BET Bromodomain Inhibitor

Gosmini, Romain, Nguyen, Van Loc, Toum, Jérôme, Simon, Christophe, Brusq, Jean-Marie G., Krysa, Gael, Mirguet, Olivier, Riou-Eymard, Alizon M., Boursier, Eric V., Trottet, Lionel, Bamborough, Paul, Cl

Journal:

Journal of Medicinal Chemistry

Year:

2014

Language:

english

File:

PDF, 963 KB

english, 2014

47

Discovery and Characterization of GSK2801, a Selective Chemical Probe for the Bromodomains BAZ2A and BAZ2B

Chen, Peiling, Chaikuad, Apirat, Bamborough, Paul, Bantscheff, Marcus, Bountra, Chas, Chung, Chun-wa, Fedorov, Oleg, Grandi, Paola, Jung, David, Lesniak, Robert, Lindon, Matthew, Müller, Susanne, Phil

Journal:

Journal of Medicinal Chemistry

Year:

2015

Language:

english

File:

PDF, 7.19 MB

english, 2015

48

Identification of a novel kinase target in DM pathophysiology

Ketley, A., Ghidelli-Disse, S., Bamborough, P., Ghosh, T.K., Sedehizadeh, S., Tang, Z., Powalowska, P., Bösche, M., Bantscheff, M., Rüdiger, M., Mossakowska, D.E., Drewry, D.H., Zuercher, W.J., Thornt

Journal:

Neuromuscular Disorders

Year:

2018

Language:

english

File:

PDF, 18 KB

english, 2018

49

3,5-Disubstituted-indole-7-carboxamides: The discovery of a novel series of potent, selective inhibitors of IKK-β

David D. Miller, Paul Bamborough, John A. Christopher, Ian R. Baldwin, Aurelie C. Champigny, Geoffrey J. Cutler, Jeffrey K. Kerns, Timothy Longstaff, Geoffrey W. Mellor, James V. Morey, Mary A. Morse,

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2011

Language:

english

File:

PDF, 883 KB

english, 2011

50

A computer model of the interleukin-4/receptor complex

Paul Bamborough, Guy H. Grant, Charles J. R. Hedgecock, Susan P. West, Dr. W. Graham Richards

Journal:

Proteins: Structure, Function, and Bioinformatics

Year:

1993

Language:

english

File:

PDF, 869 KB

english, 1993

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